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To develop small molecule inhibitors against KRAS oncogene for the treatment of cancer
January 6, 2020
By: Kristin Brooks
Managing Editor, Contract Pharma
Merck has entered an exclusive worldwide research collaboration and license agreement with Taiho Pharmaceutical Co, Ltd. and Astex Pharmaceuticals (UK), a subsidiary of Otsuka Pharmaceutical Co., to develop small molecule inhibitors against several drug targets, including the KRAS oncogene, currently being investigated for the treatment of cancer. KRAS is among the most frequently mutated oncogenes in cancer. It’s estimated to occur in more than 90% of pancreatic cancers and approximately 20%...
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